abstract |
1. 1-Phenyl-3-dimethylamino-propane compounds of the formula 1 wherein X is OH, F, Cl, H or an OCOR group with R with the meaning of C-alkyl, R is a C-alkyl group, R is H or a C-alkyl group, R is H either a linear C-alkyl group or R and Roba together represent a C-cycloalkyl radical, and if R is H, then R represents meta-OZ with Z meaning H, C-alkyl, PO (OC-alkyl), CO (OC-alkyl), CONH-CH- (C-alkyl), CO-CH-R, wherein R is ortho-OCOC alkyl or meta or para-CHN (R) with R having the meaning C-alkyl or 4-morpholino, or R is meta-SC alkyl , meta-Cl, meta-F, meta-CRRR with R, R and R having the meaning of H or F, ortho-OH, ortho-OC-alkyl, para-F or para-CRRR, or if R is always in the para-position Cl, F, OH or OC-alkyl, then R denotes always meta-position Cl, F, OH or OC-alkyl, or R and Roba together mean 3,4-OCH = CH- or 3,4-OCH = CHO-, as diastereomers or enantiomers in the form of their bases or salts of physiologically compatible acids. 2. Compounds according to claim 1, characterized in that X is OH, F, Cl or H, R is a C-alkyl group, R is H or CH and R is H or CH, and if R is H, then R is meta-OC-alkyl, meta -OH, meta-SC-alkyl, meta-F, meta-Cl, meta-CH, meta-CFH, meta-CF or para-CF or if R is always Cl or F, then R is always in meta -position of Cl or F, or R and Roba together represent 3,4-OCH = CH-. Compounds according to one of claims. 1 to 2, characterized in that the compounds of formula I, in which R and R have different meanings, are represented as their diastereomers with the configuration Ia4. The method of obtaining 1-phenyl-3-dimethylamino-propane compounds of formula I with X, representing |