| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3120ae9cab5bb4831f0cc16288966367 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-27 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4172
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 |
| filingDate |
1992-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67094d11cbb39180a527b6bdd07bc546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_639cea2b2b51058cdc78e00ab6e8ef5e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abd28cbd17a005f009e4c7e23aa511e3 |
| publicationDate |
1997-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-94045932-A |
| titleOfInvention |
Crystals of the growth hormone involving histidine or its derivatives, method of their preparing and the stabilized pharmaceutical preparation containing the growth hormone and histidine, and a method of its preparing |
| abstract |
A pharmaceutical preparation containing growth hormone and histidine or a histidine derivative as an additive or buffering agent exhibits a very high resistance to deamidation, oxidation and cleavage of peptide bonds. The stability of the product makes it possible to store and transport it in a lyophilized state or in the form of a dissolved or newly dissolved preparation at ambient temperature. Crystallization of growth hormone in the presence of histidine or its derivative leads to an increase in the yield of crystals having a higher purity than in known methods. |
| priorityDate |
1991-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |