http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-94043645-A

Outgoing Links

Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709
filingDate 1994-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e452a27ab03c6270945846ee78fbc63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ddc2b014af39522d4655217b979e6ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed2548f5fc99a256b75e7c50d2046ad2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_283650c6d0ee77575fdc1d1d433e75cf
publicationDate 1996-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-94043645-A
titleOfInvention Method of synthesis of 3-quinolonecarboxylic acid derivatives
abstract The object of the invention is a method for producing 3-quinolone carboxylic acid derivatives of the general formula 1 given in the description, which consists in reacting an acid halide of the formula 2 with an aminocrylic acid ester of the general formula 3RNH-CH = CH -COOR or first with a dimethylaminoacrylic ester acids of the general formula 4 (CH) N-CH = CH-COOR and then with the amine of the formula (5) R-NH obtained in this compound of the general formula (6) are subjected to cyclization in the presence of an alkaline agent, followed by interaction the compounds of general formula (7) with a heterocyclic compound of general formula (8) and alkaline saponification of the resulting compound of formula (9), each stage being carried out without preliminary isolation of the corresponding intermediate products, and the target product is isolated in free form or in the form salt. Formulas 1,2,6,7,8 and 9 are given in the description. The radicals A, R-R, X-X and Hal shown in formulas 1-9 have the meanings indicated in the description.
priorityDate 1993-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 26.