| abstract |
An ifetroban composition has been developed that has good solubility even after prolonged storage and has a pH of an aqueous dispersion of at least 7 that contains an ifetroban salt, one or more alkalizing agents, such as magnesium oxide or calcium carbonate, and in tablet form includes one or more excipients, such as mannitol and / or microcrystalline cellulose, one or more dispersing agents, such as crospovidone, one or more lubricating agents, such as magnesium stearate, optionally one or more e flow enhancing agents, such as colloidal silicon dioxide, one or more binding agents, such as pregelatinized starch (dry binding agent) or polyvinylpyrrolidone (wet binding agent) and optionally a film-like coating containing a film-forming agent such as hydroxypropyl cellulose and a plasticizer, such as 1,2,3-propanetriol triacetate. |