http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-80750-U1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
| filingDate | 2008-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-80750-U1 |
| titleOfInvention | TABLET |
| abstract | The utility model relates to the field of medicine, namely to new dosage forms, more precisely, to dosage forms of preparations containing 3-hydroxy-6-methyl-2-ethylpyridine succinate (mexidol or EMHPS) as an active ingredient.n n n The technical problem solved by the authors was the creation of a dosage form based on EMHPS as an active ingredient, characterized by an adjustable release rate.n n n The technical result was achieved by creating a tablet, which includes microspheres containing EMGPS and excipients, at least two of which have different dissolution rates in biological fluids.n n n This effect is achieved by using various auxiliary substances in the microgranules or by coating part of the microgranules with one or more polymer shells. Microbeads have a diameter of 0.25-2.0 mm.n n n Each microbead is a separate element that releases the drug at a predetermined rate, and their combination provides the desired in vitro dissolution profile and, accordingly, the desired plasma concentration profile and duration of action. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2444359-C1 |
| priorityDate | 2008-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.