abstract |
FIELD: pharmaceuticals. n SUBSTANCE: invention relates to duocarmycin-containing antibody-drug conjugates (ADCs) for application in treatment of HER2-expressing human solid tumours, wherein the HER2-expressing human solid tumour constitutes HER2 IHC 3+ bladder cancer, the bladder cancer is HER2 FISH-negative. n n n n EFFECT: creation of ADCs applicable in treatment of cancer. n 2 cl, 12 dwg, 1 ex |