http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2768154-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2546c3f3c2cf69e68544b45e52eac3b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-686 |
| filingDate | 2021-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4efc4e9d611ba0793031fdf90b754328 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d21ee6b4cc29775a57da810304c50807 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_517bb1a9a5d676db4823b3a15ae497f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5e02a3d1e23fce133d0feb67bb1135b |
| publicationDate | 2022-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2768154-C1 |
| titleOfInvention | Method for differential diagnosis of acute and chronic hepatitis in dogs based on cfa-mrna expression in blood serum |
| abstract | FIELD: veterinary science; biotechnology. n SUBSTANCE: invention refers to veterinary science and biotechnology, particularly to molecular hepatology. Disclosed is a method for differential diagnosis between acute hepatitis (OH) and chronic active hepatitis (CAH), as well as early prediction of hepatic fibrosis in dogs with CAH. Expression of cfa-miRNA-122 and -21 in blood serum of dogs with primary hepatitis is analyzed. Analyses are applied in triplicate for each sample, and the obtained average cycle threshold (Ct) of each tested microRNA is normalized relative to the average ct of cfa-miRNA-16 and cel-miRNA-39-3p to obtain ΔCT. When expressing cfa-miRNA-122≥1.79 acute hepatitis is diagnosed. When expressing cfa-miRNA-122≥1.64 and cfa-miRNA-21≥1.51 expression, chronic active hepatitis and hepatic fibrosis are diagnosed in dogs. n EFFECT: invention provides creation of new effective, liver-specific non-invasive diagnostic biomarkers based on genes for early diagnosis and differentiation of OH and CAH with high sensitivity and specificity in dogs with primary hepatitis. n 1 cl, 4 dwg, 1 tbl |
| priorityDate | 2021-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 182.