| abstract |
FIELD: medicine. n SUBSTANCE: present invention relates to asymmetric derivatives of dinaphthalene polyphenols of the general Formula (I) or the general Formula (II) , to their production methods and to their use as antiviral agent effective relatively to influenza A virus. In the formula I, R 1 is: C(O)H, CH=N-R 8 , where R 8 is: linear and branched C 1 -C 20 alkyl substituted with phenyl; R 2 , R 3 , R 3a , R 5 , R 5a , R 7 , R 7a are H; R 2a is: H, linear and branched C 1 -C 20 alkyl substituted with COOR 8a , where R 8a is: H, linear and branched C 1 -C 20 alkyl; R 4 , R 4a , R 6 and R 6a are independently linear and branched C 1 -C 10 alkyl. In the formula II, R 1 is: C(O)H; R 2 , R 3 , R 2a , R 3a are H; R 4 , R 4a , R 6 and R 6a are independently H, linear or branched C 1 -C 10 alkyl. n EFFECT: obtaining an antiviral agent for the treatment of influenza A virus. n 16 cl, 5 dwg, 2 tbl |