abstract |
FIELD: biotechnology. n SUBSTANCE: invention relates to the field of biotechnology, in particular, to a monoclonal antibody or an antigen-binding fragment thereof, capable of specifically binding to human alpha-synuclein, as well as to an agent, a composition, and a conjugate containing said antibody or fragment. Also disclosed are a nucleic acid encoding said antibody or a fragment thereof. n EFFECT: invention is effective for treating synucleopathy, for identifying the presence of alpha-synuclein in the brain of the subject, as well as for measuring the amount of alpha-synuclein in the brain of the subject. n 56 cl, 27 dwg, 4 tbl, 11 ex |