abstract |
FIELD: biotechnology.SUBSTANCE: invention relates to the field of biotechnology, in particular to an isolated antibody specifically binding an extracellular domain of the human and mouse inducible T-cell co-stimulator (ICOS), as well as to a composition containing it. A host cell in vitro for the expression of the above-mentioned antibody is also disclosed.EFFECT: invention is effective for the stimulation of a T-cell immune response, as well as for the treatment of cancer.26 cl, 45 dwg, 32 tbl, 26 ex |