abstract |
FIELD: medicine. n SUBSTANCE: present invention relates to a class of cyclopropylamine compounds, namely to a compound of the formula (I), its pharmaceutically acceptable salt or its tautomer, n n n n where values of f, r, e, p, m, n, R 1 , R 2 , R 3 , R 4 and R 6 are such as defined in the formula of the invention. Pharmaceutical compositions and the use of a compound of the formula (I) in the manufacture of LSD1 inhibitors and a drug for the treatment of lung cancer are also proposed. n EFFECT: obtaining new organic compounds that are inhibitors of lysin-specific demethylase 1 (LSD1). n 29 cl, 8 tbl, 246 ex |