http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2760677-C1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ade3817c5b502f291de81c30c2c92a5 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-43 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 2020-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cef745a8c9414941c191bbf92a4cb1c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a49838e47f2ce860ef43600febc04d26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_363e69ae10548ff327c65793ef9a977f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd0ea21680ab8f4bfc9fcab0556f5238 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31c2a3f0d9d4554f94ceda59cbe9af18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab1e9d43cc8891817627ef73449a1410 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c8e69ed9c88e42ac9b6852137b515f0 |
publicationDate | 2021-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2760677-C1 |
titleOfInvention | APPLICATION OF Fe-Fe 3O4 NANOPARTICLES WITH A CORE-SHELL STRUCTURE TO INCREASE THE SENSITIVITY OF BACTERIA TO ANTIBIOTICS |
abstract | FIELD: medicine.SUBSTANCE: invention relates to the field of medicine and pharmaceuticals, namely, to an application of Fe-Fe3O4(iron-iron oxide) nanoparticles with a core-shell structure, wherein the core is Fe and the shell is Fe3O4, as a means of increasing the sensitivity of bacteria of resistant strains such asPseudomonas aeruginosaandStaphylococcus aureusto antibiotics such as ampicillin and amikacin, in treatment of wounds, wherein the nanoparticles are selected from 1) those with a positive zeta potential in deionised water at a pH of 7.4 and a temperature of 37°C of 9.6±1.8 mV, the value of the specific surface area of 6.7±0.9 m2/g, the content of iron oxide (Fe3O4) of 39 wt.%, and the average particle size of 81±5 nm or 2) those with a positive zeta potential in deionised water at a pH of 7.4 and a temperature of 37°C of 10.4±2.3 mV, the value of the specific surface area of 7.3±0.8 m2/g, the content of iron oxide (Fe3O4) of 92 wt.%, and the average particle size of 78±3 nm.EFFECT: reduced dosage of the antibiotic, possibility of applying low-toxic antibiotics, increased effectiveness of treatment.7 cl, 5 tbl, 2 ex |
priorityDate | 2020-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.