http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2760438-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_097dabeb01fa92d348ba39db560f625a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-52 |
| filingDate | 2021-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_298fef77b3c6b122d0ff75d5ea89f1bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f2c7be9f925f79804b6631ca25f234c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc234353b7ad21ad6ee81292616210d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d10a219f8b8eca69eb137f35d0e3b9cc |
| publicationDate | 2021-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2760438-C1 |
| titleOfInvention | METHOD FOR ENZYME IMMUNOASSAY DETERMINATION OF THE LEVEL OF ANTIGEN-RECOGNIZING B-LYMPHOCYTE RECEPTORS REPRESENTED BY MEMBRANE-SPECIFIC RBD PROTEIN SARS-COV-2, IgG ANTIBODIES |
| abstract | FIELD: biotechnology. n SUBSTANCE: proposed is method of enzyme immunoassay determination of the level of antigen-recognizing B-lymphocyte receptors represented by membrane antibodies specific to RBD Protein SARS-CoV-2, IgG. The method includes applying a recombinant RBD protein to the wells of the microplate corresponding to the structure of the RBD protein epitope of the SARS-CoV-2 virus, introducing calibration samples containing known amounts of IgG into the wells of the microplate, isolating and bringing the suspension of lymphocytes to the working concentration, introducing a suspension of lymphocytes into the wells of the microplate with antigen, introducing an IgG antibody conjugate, introducing TMB chromogen, conducting a color reaction, optical density spectrophotometry, construction of a calibration curve and determination of the concentration of SARS-CoV-2 IgG virus specific to RBD protein-antibodies relative to the optical density of calibration samples in the reference system. n EFFECT: invention makes it possible to detect in an infected person who has undergone COVID-19 or vaccinated, the level of specific neutralizing IgG antibodies to the RBD epitope of coronavirus, potentially characterizing the activity of B-lymphocyte receptors. n 1 cl, 4 tbl |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2781235-C1 |
| priorityDate | 2021-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.