http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2759054-C2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3226ef2e62cab3eb1cd4933252bf91e7 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-145 |
filingDate | 2019-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ed52a3098b0f4b8beab23fae4b2642a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cff8a591fae61171b667a9a424a1f36e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9fc66003c04676f14308067dd4bcc91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56831a6a434d1222773232e824981923 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08571d66772548d89bc4fa7cbf06dbbe |
publicationDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2759054-C2 |
titleOfInvention | RECOMBINANT STRAIN OF A/PR8-NS124-Luc INFLUENZA VIRUS AND METHOD FOR EVALUATING POST-VACCINAL NEUTRALIZING ANTIBODIES USING BIOLUMINESCENT DETECTION |
abstract | FIELD: biotechnology; virology; medicine.SUBSTANCE: recombinant virus of A/PR8-NS124-Luc influenza, Orthomyxoviridae family, Influenza virus A genus, H1N1 subtype expressing NanoLuc protein as part of open reading frame of shortened NS1 protein deposited in the State virus collection under No.2906 is described. A method for quick evaluation of neutralizing activity of antibodies in RDE processed blood serum using a recombinant influenza virus A expressing NanoLuc protein as part of open reading frame of shortened NS1 protein is presented.EFFECT: invention allows for detection of the development of influenza infection in living biological systems and quick evaluation of neutralizing activity of antibodies and antiviral activity of chemical preparations.5 cl, 10 dwg, 3 tbl, 6 ex |
priorityDate | 2019-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 244.