http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2757961-C2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
filingDate | 2015-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e27f47ef1bf6265ce5ee2da06b6fc9ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d02e4b98e42a7a4883de0f2a1ae9985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5740d5f990b8ddf7ee469bda806e2db5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94067a418537429f9955bb13afa84fed |
publicationDate | 2021-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2757961-C2 |
titleOfInvention | Method for treating multiple sclerosis |
abstract | FIELD: medicine.SUBSTANCE: group of inventions relates to a method for improving functional capacity in a patient having multiple sclerosis, comprising administering to the patient an effective amount of anti-CD20 antibody, wherein the patient has improved functional capacity after administration and where the functional capacity improvement is maintained for at least 12 weeks; where anti-CD20 antibody contains: a) a heavy chain variable region comprising CDR1 having the amino acid sequence SEQ ID NO: 10, CDR2, having amino acid sequence SEQ ID NO: 11, and CDR3 having the amino acid sequence SEQ ID NO: 12, and b) a light chain variable region containing CDR1 having the amino acid sequence SEQ ID NO: 4, CDR2 having the amino acid sequence SEQ ID NO: 5, and CDR3, having amino acid sequence SEQ ID NO: 6. Group of inventions also relates to a method of reducing the average annual recurrence rate in a human patient having multiple sclerosis; kit for treating multiple sclerosis in a patient in accordance with said method.EFFECT: group of inventions provides improved functional capacity in the patient suffering multiple sclerosis.58 cl, 34 dwg, 14 tbl, 2 ex |
priorityDate | 2015-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 2474.