http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2756197-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4cdc4e762c77015fb9906e8c8a461731 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D459-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 |
| filingDate | 2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31b219d8e925730bb005a38c0345d737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9f3486e6839e6046dd3f8aefd051e39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cdf511ea8f4cdcc89ccb831dbbdbd3e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3430002bf650128a9125422c61b0811c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de2c92d25c93a3977fc129fc72db579b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b17e4178e144d37c449f52cc3f2e10e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7329e4f5986ba772a2acaca45dc04e1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a522264f1c1c79293d533e5f07a7e1c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddf8b28f45d6906ef68c3deab77c3fe9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fca4439ed0856bab67a21d9f682132df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1652f8adfbef06b246f80c346fb20dc9 |
| publicationDate | 2021-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2756197-C2 |
| titleOfInvention | Phenyl [a]indole [2,3-g] quinolysins, their preparation method, compositions containing them and application options |
| abstract | FIELD: pharmaceutics.SUBSTANCE: invention relates to a condensed heterocyclic compound of the general formula (I) or its enantiomer, diastereomer, racemate and mixture thereof, where R1and R2are each independently selected from a group consisting of hydrogen, substituted or unsubstituted C1-C4 alkyl, substituted or unsubstituted C6-C10 aryl; and R1and R2are not both hydrogen or R1and R2and neighboring -(CH2)n-O and bound carbon atoms together form unsubstituted 5-element heterocyclic ring, wherein the specified heterocyclic ring is thiophene; each R3, R4is independently selected from a group consisting of hydrogen, substituted or unsubstituted C1-C6 alkyl, substituted or unsubstituted C6-C10 aryl, substituted or unsubstituted 5-element heterocyclic ring, which is selected from thiophene, furan and pyrrole, unsubstituted benzyl, -SO2R9; R5is selected from a group consisting of hydrogen or halogen; R6and R7are each independently selected from a group consisting of hydrogen, unsubstituted C1-C2 alkyl, unsubstituted C1-C2 alkoxy, -OSO2R9; R8is hydrogen; R9and R10are independently hydrogen, unsubstituted C1-C6 alkyl or unsubstituted C6 cycloalkyl, C6-C10 aryl unsubstituted or substituted with 1 halogen, benzyl; wherein, if both of R3and R4are hydrogen, then at least one of R1, R2, R6, R7is a group selected from a group consisting of substituted C6-C10 aryl; where “substituted” means that one, two or three hydrogen atoms in the group are substituted by a substituent selected from a group consisting of halogen, C1-C2 alkyl unsubstituted or substituted with three halogens, C1 alkoxy, hydroxy, cyano, unsubstituted 5-element heterocyclic ring selected from pyrazole, -NR9R10, -SO2R9, -OSO2R9, -COOR9and -OCOR9; n is 1. The invention also relates to specific condensed heterocyclic compounds, a method for obtaining a compound of the formula (I) and a pharmaceutical composition based on a compound of the formula (I).EFFECT: obtaining of a new condensed heterocyclic compounds useful for the treatment of metabolic diseases.13 cl, 6 tbl, 414 ex |
| priorityDate | 2016-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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