| abstract |
FIELD: pharmaceutics.SUBSTANCE: present invention relates to a pharmaceutical composition for the treatment and/or prevention of malignant tumor expressing MCEMP1 on a cell surface, which contains, as an active ingredient, effective amount of an antibody having immune reactivity with polypeptide containing a part of extracellular area of MCEMP1 protein, where polypeptide is polypeptide consisting of 7 or more subsequent amino acids of amino acid sequence represented in SEQ ID NO: 10. The present invention also relates to a method for the treatment and/or prevention of malignant tumors expressing MCEMP1 on the cell surface, which includes injecting a patient by parenteral injection effective amount of the antibody having immune reactivity with polypeptide containing the part of extracellular area of MCEMP1 protein, where polypeptide is polypeptide consisting of 7 or more subsequent amino acids of amino acid sequence represented in SEQ ID NO: 10.EFFECT: use of antibodies to MCEMP1 for treatment or prevention of malignant tumors.5 cl, 4 dwg, 4 ex |