http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2754075-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79ae6dd5bafbd2dd69035367385d754c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B17-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B17-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 |
| filingDate | 2020-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f95a931206870fc9c5c69afd90b45e5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f355da37c0f44fd69559d02afd85d7c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e322105cb3064c8e44c18dd70d30e02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e779e585d2b4bc0de613e0de8a516c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fe4d64484deb181554629811c87bfb0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c3525ac52ba991d74a7d7b53f5f3832 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b30f645f8c05e214cf1779cc06f17dd6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9f8db31837e02547ba3d81a4893685d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_087e17808e8a62e99da21158db7c7ebd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed97644aedab553ec769f50aee6bb116 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11d23269cd411355b563d6b2372cdaaa |
| publicationDate | 2021-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2754075-C1 |
| titleOfInvention | Method for manufacturing a cement spacer for etiotropic local antibacterial therapy for infectious affections of bones and joints |
| abstract | FIELD: medicine.SUBSTANCE: invention relates to medicine, in particular to surgery, and can be used in traumatology and orthopedics, namely, to a method for manufacturing a cement spacer for etiotropic local antibacterial therapy for infectious affections of bones and joints. The method involves mixing a polymethylmethacrylate powder of bone cement containing gentamicin with a broad-spectrum antibiotic and with Poviargolum. At the same time, an individually selected water-soluble thermostable antibiotic in the amount of 10 wt. % is additionally injected intraoperatively into the bone cement with gentamicin in the form of a powder and, with the necessary duration of antimicrobial activity for 21 days, Poviargolum powder is used in an amount of 2.5 wt. % or in the amount of 10 wt. % if the required duration of antimicrobial activity is more than 21 days. Then a liquid monomer of bone cement based on methyl methacrylate is added and mixed until a paste of a dough-like consistency is obtained, after which the spacer components are made.EFFECT: ensuring the possibility of individual selection of local etiotropic antibacterial therapy, the implementation of the necessary duration of effective antimicrobial action of the spacer, the prevention of the formation of microbial biofilms on the surface of the structure, as well as the elimination of technical problems when removing the implant at the stages of surgical treatment while maintaining sufficient strength characteristics of the spacer.1 cl, 2 ex, 4 dwg |
| priorityDate | 2020-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.