| abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to new biologically active compounds, namely to arylmethylene bispiran-2-one-based complex compounds of copper (II), of the formula n , n wherein at n = 4, R = H (1) or R = 3-NO 2 (2) or at n = 3, R = 4-OCH 3 (3). n EFFECT: proposed complex compounds exhibit a cytotoxic effect, particularly, the ability to suppress metabolic activity of the human cervical carcinoma (HeLa) cell line, and are potentially applicable in medical practice for treatment of cancerous diseases. n 1 cl, 3 dwg, 1 tbl, 4 ex |