http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2752906-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93529a9839a064708dedcbea2b786417 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-095 |
| filingDate | 2019-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e97e7ac92b2881fbf7db15b527ecb225 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c3a7d76b816f391386dd251f1a423a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e707cd51ec81f7171332249a959c6496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5f09c5c6e1ccafcb217c4fe876b8533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dc1fea164ed5dd18b6160004ef11be6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_061d9600460ffbf95d59d46d4227681e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00f451dc1b8b333520849c039166667f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60ccc25abf332cff9c838797f7c84f4f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28a659d6c32035dcb68afe5bc191da79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9719238a5389798f7ea273953bfa5d02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_273a39fd6eff2dfe847754c617e83485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c1a6b9fb4cb067fb340352d4c774c2e |
| publicationDate | 2021-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2752906-C2 |
| titleOfInvention | Nootropic composition based on polypeptide complexes isolated from neuronal progenitor cells under heat shock and method for production thereof |
| abstract | FIELD: biotechnology.SUBSTANCE: invention relates to the field of biotechnology, particularly to a method for producing a nootropic composition based on polypeptide complexes isolated from neuronal progenitor cells under heat shock. Said composition is characterised by the fact that it contains proteins and polypeptides with a molecular weight from 3 kDa to 250 kDa, 60% whereof have a molecular weight in the range from 10 to 50 kDa, brain-derived neurotrophic factor (BDNF) no less than 120 pg/ml, and glial cell line-derived neurotrophic factor (GDNF) no less than 40 pg/ml, vascular endothelial growth factor (VEGF) not less than 60 pg/ml, total protein weight no less than 1 mg/ml of the preparation. The cell culture of neuronal progenitor cells therein, wherefrom the composition is produced, demonstrates the expression of a β3-tubulin neuronal marker, a nerve cell adhesion molecule (PSA-NCAM), and consists of 99.5±2.45% TUBB3+cells.EFFECT: invention allows effectively producing a protein-peptide composition including not only small peptides, but also full-size protein neuronal growth and differentiation factors the effectiveness whereof is invariably higher than in short peptides and immunogenicity is not present.2 cl, 2 dwg, 4 ex |
| priorityDate | 2019-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 500.