http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2752872-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68235a5e3014d64e15d3c31ce7860832 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D11-02 |
| filingDate | 2020-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47d87a7c711b9ac3fe05959af0acb8cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7916462434a95948d54b9bc90d67cf1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e52612b49674c93aa85d41f01b0b93f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94587fdb19192ed01fec4cd13e36abdf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cb5fbad525cc8979f9ed92b5c15ba30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_008e091d1d78b2f244884271b584e3b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3165934f045ee2ccbfd7d79381c0591c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edfacbb992a778430337e56b1ad2452b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1a49075d72c4776e7a5f6283ae58c5f |
| publicationDate | 2021-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2752872-C1 |
| titleOfInvention | SARS-CoV-2 CORONAVIRUS REPLICATION INHIBITOR BASED ON HUMIC SUBSTANCES |
| abstract | FIELD: pharmaceutical industry.SUBSTANCE: group of inventions relates to the pharmaceutical industry, namely to the use of water-soluble humic substances from brown coal or from chaga to inhibit the replication of the SARS-CoV-2 coronavirus. The use of water-soluble humic substances from brown coal obtained as a result of the exothermic reaction of crushed brown coal in a mixture of 2% ammonia and hydrogen peroxide, followed by precipitation and re-precipitation of humic substances with hydrochloric acid, dilution in water at pH 7.0-8.0, drying, with or without trypsin treatment, to inhibit the replication of the SARS-CoV-2 coronavirus, which, at concentrations in the range of 14.34-23.1 mcg/ml, exhibit a 50% antiviral dose-dependent activity against SARS-CoV-2 in tests on Vero cell cultures. The use of water-soluble humic substances from the chaga, basid fungus Inonotus obliquus, obtained as a result of the exothermic reaction of crushed chaga in a mixture of 2% ammonia and hydrogen peroxide, followed by precipitation and re-precipitation of humic substances with hydrochloric acid, dilution in water at pH 7.0-8.0, drying, treatment with trypsin, to inhibit the replication of the SARS-CoV-2 coronavirus, which at a concentration of 23.447 mcg/ml exhibit 50% antiviral dose-dependent inhibitory activity against SARS-CoV-2 in Vero cell culture tests.EFFECT: above-described use of humic substances is effective for inhibiting the replication of the SARS-CoV-2 coronavirus.2 cl, 1 dwg, 1 tbl, 8 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2793414-C1 |
| priorityDate | 2020-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 153.