http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2750902-C1

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filingDate 2020-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a470ea734884506d166fe76dd80c5a4
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publicationDate 2021-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2750902-C1
titleOfInvention Corneal collagen crosslinking and simultaneous implantation of intrastromal corneal segments in the paired eye in patients with different stages of keratoconus
abstract FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to ophthalmology. Cross-linking is performed only on one eye, while intrastromal corneal segments are implanted simultaneously on the paired eye, and the treatment of the operating field and the instillation of antibacterial and anesthetic drops are carried out on both eyes simultaneously for 2-3 minutes. Then, on the first eye, de-epithelialization of the cornea with a diameter of 8.5 mm is performed for 1 minute. Then, for 30 minutes on the first eye, the stroma is impregnated with a 0.1% solution of riboflavin mononucleotide and dextran by instillations 1 time per minute for 30 minutes. At the same time, a 360° intrastromal corneal tunnel is formed on the paired eye by femtodissection of the corneal stroma at a depth of 80% of the corneal thickness. An entrance incision is also formed for the introduction of an intrastromal corneal segment, and a 1.0-1.3 mm long incision is made perpendicular to the formed corneal tunnel, asymmetrically from the planned installation of the corneal segment, and the corneal segment is installed so that its edges are as far as possible from the zone of the entrance incisions. After that, in the next 30 minutes, the cornea of ​​the eye is irradiated with ultraviolet light on the first eye, and a riboflavin solution is instilled with a frequency of 1 every 3-5 minutes. The operation ends with the imposition of soft contact lenses.EFFECT: method increases the efficiency of treatment of a patient with different degrees of keratoconus while reducing the duration of treatment and ensures safety and convenience for the ophthalmic surgeon.1 cl, 3 ex
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