| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c594aa2a8aed0f79f311a94eed981c32 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 |
| filingDate |
2019-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d63b7e2a5296c49b615529cd2a853a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ede0602818a9846564dcdf7ed2e44976
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf36402e329a80da47972393e7dc3cf1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a1c4d9b02d9023432cd92db52c38fd4 |
| publicationDate |
2021-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2750761-C2 |
| titleOfInvention |
Cinacalcet hydrochloride tablet core |
| abstract |
FIELD: pharmaceuticals.SUBSTANCE: invention relates to pharmaceutical compositions and dosage forms containing cinacalcet hydrochloride (CCH). Proposed is a tablet core containing, as an active principle, a complex of cinacalcet hydrochloride with hydroxypropyl cellulose, obtained by introducing cinacalcet hydrochloride with vigorous stirring into a saturated aqueous methanol solution of hydroxypropyl cellulose at a temperature of 40-60°C with a cinacalcet hydrochloride content of 46-63 wt %, with the following ratio of ingredients in the final product (wt %): silicon dioxide 0.5-2; magnesium stearate 0.5-2; complex of cinacalcet hydrochloride with hydroxypropyl cellulose - the rest.EFFECT: claimed composition of the tablet core ensures the solubility of CCH more than 90% at acidic and neutral pH.2 cl, 1 tbl, 3 ex |
| priorityDate |
2019-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |