| abstract |
FIELD: pharmaceuticals. n SUBSTANCE: invention relates to a pharmaceutical composition based on 6-amino-9-[(3R)-1-(2-butinoyl)-3-pyrrolidinyl]-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purine-8-one hydrochloride, which has the activity of a selective Btk inhibitor, useful for the prevention and/or treatment of Btk-related diseases. The invention also relates to the use of 6-amino-9-[(3R)-1-(2-butinoyl)-3-pyrrolidinyl]-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purine-8-one hydrochloride. n EFFECT: pharmaceutical composition based on a Btk inhibitor has been obtained that is useful for the treatment of non-Hodgkin's lymphoma, autoimmune disease, and other Btk-related diseases. n 6 cl, 4 dwg, 6 tbl, 15 ex |