http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2746100-C1

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grantDate 2021-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2021-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2746100-C1
titleOfInvention Method of multiplex detection of toxin genes
abstract FIELD: medicine; microbiology. n SUBSTANCE: method of multiplex detection of toxin genes is proposed. At the first stage, DNA-libraries synthesis is carried out. At the second stage, the targeted enrichment of DNA-libraries molecules carrying sections of the analyzed toxin genes is carried out using method of liquid hybridization of DNA-probes. Quantification of the amplified DNA-libraries is carried out for the following NGS sequencing using fluorimetric method. n EFFECT: invention provides increase in relative representation of target sections of the toxin genes in the final DNA mix analyzed with high-performance sequencing methods in compare with incoming DNA. n 1 cl, 1 tbl
priorityDate 2019-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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