http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2745996-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0bf0928b608797b70bbc2b91c7e52e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q11-00 |
| filingDate | 2016-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9113addb7e37af9331e9b0b7366a9316 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3231451378c1c1a9caa1238d6bb650c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91e426b787e6802e27e3926586597fd9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_485e6159052e57e8d3926225725dbf68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02cfa8e126682c8b3e69d74e1c4cf43d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c90383482d9915c23f03b866146a010 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12f420015718b772e66b205f4f4a597b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0c9e7d72f8160ba58481120bfaeca0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a53bcb9c0998f4444a8a52b7d3a50e9a |
| publicationDate | 2021-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2745996-C2 |
| titleOfInvention | Oral care products and methods containing hydroxyapatite-binding proteins |
| abstract | FIELD: oral care.SUBSTANCE: group of inventions relates to methods and compositions using hydroxyapatite-binding polypeptides (HABP). A method of binding to the enamel and/or dentin surface or targeting the enamel and/or dentin surface of HABP is proposed, comprising applying to the tooth an oral composition containing: а) HABP having a polypeptide sequence according to the formula (I)wherein a, d are independently a hydrophobin or an antifreeze protein sequence or an active ingredient for oral care, b, с independently of each other are an amino acid, y is a polypeptide sequence according to SEQ ID NO: 1 to SEQ ID NO: 16; b) orally acceptable carrier, wherein HABP is present in the composition in an amount from 0.01 wt% up to 3 wt% of the total mass of the composition. Also proposed are: a dental cleaner, an oral care composition for restoring or inhibiting erosion of tooth enamel and a chewing gum composition containing the said HABP; and using the HABP for preparing an oral care composition for restoring or inhibiting dental erosion. A method is proposed for the preparation of an oral care product containing the specified (HABP), including a) neutralization of the HABP solution by diluting with an aqueous buffer solution to obtain a solution having an almost neutral or slightly basic pH value; b) filtering and centrifuging the product solution according to a) producing a HABP-containing filtrate; c) adding fluoride to product filtrate b); d) admixing product c) to the components of an orally acceptable carrier, and an oral composition thus obtained. Also proposed are hydroxyapatite-binding polypeptides, including SEQ ID NO: 1, 2, 3, 4, 6, 8, 16.EFFECT: НАВР used are effective in restoring or mitigating the effects of dental erosion; they promote dental remineralization and enhance anti-carious effects of fluoride.17 cl, 1 tbl, 7 ex |
| priorityDate | 2015-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1035.