abstract |
FIELD: organic chemistry. n SUBSTANCE: invention relates to the field of organic chemistry, in particular to a heterocyclic compound of formula I or to a pharmaceutically acceptable salt thereof where X is -O-; Y is or ; each R 1 and R 2 is hydrogen; each R 3 and R 4 is independently selected from hydrogen and halogen, and when one of R 3 or R 4 is a halogen, the other of R 3 or R 4 is hydrogen; R 5 is a C 1 -C 6 alkyl or C 1 -C 6 haloalkyl; R 6 is a C 1 -C 6 haloalkyl; and each R 7 and R 8 is independently selected from hydrogen and C 1 -C 6 6alkyl. The invention also relates to a pharmaceutical composition based on a formula I compound and to a method for treating an estrogen-mediated disruption, which involves introducing a formula I compound. n EFFECT: technical result is that new heterocyclic compounds have been produced, useful for the treatment of certain cancers, such as breast cancer, ovarian cancer, etc. n n n n 47 cl, 11 dwg, 4 tbl, 21 ex |