http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2745161-C1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_23afbaf9885ffdfa029bf0f887ab502c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
filingDate | 2019-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca1378669b33a503d08e8fd73868599a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec17f9f7cef11c4c94d8f6efb1ede6f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d0871009b72acfd0a14a3a5c2b7342d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00738dcd44badf6ae13d91074a3a7c37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cd28db46217124ce3555884daeab483 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_241775ea6bcc18a10dce502580763236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7528558215e5c42c7633c4ef6c35e7de |
publicationDate | 2021-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2745161-C1 |
titleOfInvention | Method of obtainig an attenuated plasmid-free strain of f.tularensis 15 cmsa, synthesizing mycobacterial antigen superoxide dismutase a |
abstract | FIELD: biotechnology. n SUBSTANCE: invention relates to the field of biotechnology. A method for obtaining a strain is proposed. The strain is obtained from the F. tularensis 15 NIIEG vaccine strain by allelic exchange of one of two copies of the iglC gene for a recombinant operon consisting of the groE promoter region of the F. tularensis operon, the fopL leader sequence of the F. tularensis fopA gene, and the structural part of the modified M. tuberculosis sodA gene. n EFFECT: invention makes it possible to obtain an attenuated F. tularensis strain that synthesizes the mycobacterial antigen superoxide dismutase A. to study the prospects for using the strain in the development of a live combined tuberculosis-tularemia vaccine. n 1 cl, 15 dwg, 1 tbl, 10 ex |
priorityDate | 2019-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 234.