http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2742770-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a36c66685971b78daf233b5999ead4c2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-06 |
| filingDate | 2018-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9255f3d8de3d968fb12780d85cea327d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5e887eecbae3a3db2411624e08b1624 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd9f8b8f1bb7ecc36d421418f2d4319c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f700c2048ec9e12d87691d1a5019da33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6f3ec43fb82a35323aa84257c12ffdc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a86dfb8b8da942fb6c1517c20266325d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f06a91309547053a18d2482fde98baa4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_137049a4ec346820da84b1f00f3d94ef |
| publicationDate | 2021-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2742770-C1 |
| titleOfInvention | Indole derivative and formamide, method for production thereof and use in medicine |
| abstract | FIELD: chemistry.SUBSTANCE: invention relates to a compound of formula (I) or pharmaceutically acceptable salts thereof, wheredenotes a double or single bond, G1, G2and G3are identical or different, each independently selected from a group consisting of C, CH, CH2and N, Ring A is selected from a group consisting of phenyl, pyridyl, imidazolyl, pyrazolyl and morpholinyl, each of R1is identical or different, wherein each is independently selected from a group consisting of hydrogen, halogen, C1-6alkyl, C1-6haloalkyl, C1-6alkoxy, C1-6haloalkoxy, cyano, amino, nitro, hydroxy and C1-6hydroxyalkyl, R2is C1-6haloalkyl, R3is selected from a group consisting of C1-6alkyl, C1-6haloalkyl, C1-6alkoxy, C1-6haloalkoxy, C1-6hydroxyalkyl, halogen and hydroxy, each of R4is identical or different, each being independently selected from a group consisting of hydrogen, halogen, C1-6alkyl, C1-6haloalkyl, C1-6alkoxy, C1-6haloalkoxy, cyano, amino, nitro, hydroxy and C1-6hydroxyalkyl, R5is selected from a group consisting of hydrogen, C1-6alkyl, C1-6haloalkyl, amino, hydroxy, C1-6hydroxyalkyl, 3−6-member cycloalkyl and NR10R11, where each of C1-6alkyl and 3−6-member cycloalkyl is independently optionally substituted with one or more substitutes selected from a group consisting of hydroxy, halogen, C1-6alkyl, amino, 3−6-member cycloalkyl and 3−6-member heterocyclyl, each of R6is identical or different, each being independently selected from a group consisting of hydrogen, halogen, C1-6alkyl, C1-6haloalkyl, C1-6alkoxy, C1-6haloalkoxy, cyano, amino, nitro, hydroxy and C1-6hydroxyalkyl, R7is selected from a group consisting of hydrogen, C1-6alkyl, C1-6haloalkyl and 3−6-member cycloalkyl, where C1-6alkyl is optionally substituted with one or more substitutes selected from a group consisting of halogen, nitro and 3−6-member cycloalkyl, R8and R9are identical or different, each being independently selected from a group consisting of hydrogen, halogen, C1-6alkyl, C1-6haloalkyl, C1-6alkoxy, cyano, amino, nitro, hydroxy and C1-6hydroxyalkyl, R10and R11are identical or different, each being independently selected from a group consisting of hydrogen, C1-6alkyl, C1-6haloalkyl, amino, hydroxy, C1-6hydroxyalkyl and 3−6-member cycloalkyl , n equals 0 or 1, s equals 0 or 1, and t equals 0 or 1.EFFECT: technical result is obtaining novel compounds of formula (I), which can be used in medicine for treating tumor diseases mediated by RORγ.13 cl, 2 tbl, 1 dwg, 17 ex |
| priorityDate | 2017-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 236.