| abstract |
FIELD: organic chemistry.SUBSTANCE: invention relates to a heterocyclic compound of formula IV or a pharmaceutically acceptable salt thereof, wherein L1-L2is, where R1is a substitute for nitrogen; Z is -NH-; R1is selected from:and; R2is methylpyridinyl or trifluoromethylpyridinyl; R4denotes hydrogen; R5, R6and R7are selected from hydrogen, halogen and -OR1a, provided that one of R5, R6and R7is -OR1a; and R1ais selected from trifluoromethyl,. Invention also relates to specific compounds of formulas D1 and D8, a pharmaceutical composition based on said compounds and a method of treating, preventing or alleviating said diseases.EFFECT: obtaining novel benzimidazole derivatives effective in treating cancer.15 cl, 2 tbl, 30 ex |