http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2741709-C1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c3a596e94e0b239db75421f823bf5c72 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-487 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-487 |
filingDate | 2020-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0284b84728fa0bf75e708ef9b8c7867a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa85e1da3e7ee9324ce9e5ab53416c97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2dbbf256eff5b4ad940332117c9d84c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_614e28a4445595560a87301d6298aaef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_640e67a478546c754800626161f1603b |
publicationDate | 2021-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2741709-C1 |
titleOfInvention | Method for assessing the oropharyngeal dysbiosis in children |
abstract | FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to clinical laboratory diagnostics, and can be used for evaluating the oropharyngeal dysbiosis in children. Content of acetic, propionic, isobutyric, butyric and caproic acids is determined in the saliva of a child by gas-liquid chromatography. Then, using classification equations of linear discriminant analysis, the value of diagnostic coefficients evaluating the dysbiosis state is calculated by formulas F1=12210.91*C2+11890.28*C3+13156.14*iC4+12226.24*C4+42514.51*C6-6025.33, F2=12015.23*C2+11738.47*C3+12952.92*iC4+12062.53*C4+41838.19*C6-5846.01, where F1is the diagnostic coefficient, at the maximum value of which the oropharyngeal dysbiosis is established; F2is the diagnostic coefficient, at the maximum value of which the oropharyngeal dysbiosis is not established; C2 is relative concentration of acetic acid; C3 is relative concentration of propionic acid; iC4 is isobutyric acid relative concentration; C4 is the relative concentration of butyric acid; C6 is relative concentration of caproic acid. If F1is more than F2, oropharyngeal dysbiosis is established, and if F1is less than F2, absence of oropharyngeal dysbiosis is established.EFFECT: method provides fast and reliable assessment of oropharyngeal dysbiosis in children by identifying a specific ratio of concentrations of single-chain fatty acids in saliva, that allows to take into account changes in all loci of oropharyngeal biotope and change of anaerobic part of microbiocenosis.1 cl, 2 ex |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2768491-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2803483-C2 |
priorityDate | 2020-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.