http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2741689-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_404dc008abd1734959929e0bf612536e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G09B23-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G09B23-28 |
| filingDate | 2020-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a8f567e15fcc1170734ba6c2c1a3d8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00f1de008a180d9d55384a5a001105a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_477ecde39a7712f260ac0627ed5282c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_775612f6407eb7a75bd9d16ded42f44a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05ed646e2b8736df3dd7abc65b216bb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02580337e90d2c511f97b010dfc9e384 |
| publicationDate | 2021-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2741689-C1 |
| titleOfInvention | Method of optimization of oxygen-dependent processes with prolonged administration of simvastatin to animals with using lipoic acid |
| abstract | FIELD: biology; medicine.SUBSTANCE: invention relates to experimental biology and medicine and can be used for optimization of oxygen-dependent processes with prolonged administration of simvastatin to animals. That is ensured by inducing essential hypercholesterolemia in outbred male rats, and then animal once a day for two months receives simvastatin 20 mg and lipoic acid 600 mg in a therapeutic dosage in terms of 100 g of a mass in the form of an aqueous suspension through an esophageal probe.EFFECT: method enables eliminating side effects associated with depression of energy processes accompanying prolonged simvastatin therapy by reducing the level of lactate and changing the glutathione link enzyme indices, which indicates antioxidant protection reorganization.1 cl, 1 tbl |
| priorityDate | 2020-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.