http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2739834-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71b944100daf03103e6704d7474fd127 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-108 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D257-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-00 |
| filingDate | 2016-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5de32e3c484a068301c9d6fb5723eaf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26af1d3be53ce309af2169b415eb6006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8793e6319adb328d35dcb34993e823e3 |
| publicationDate | 2020-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2739834-C2 |
| titleOfInvention | Dimeric contrast agents |
| abstract | FIELD: pharmaceuticals.SUBSTANCE: invention relates to a compound of formula (I), in which R is -CH(R1)-COOH, R 1 is H; n is 1; R2is selected from a group consisting of: C1-C5alkyl substituted with one or more C3-C8hydroxyalkoxy groups; a group of formula -(CH2)sCH(R3)-G; and C5-C12hydroxyalkyl containing at least 2 hydroxyl groups; s is 0; R 3 is H; G is a group selected from -PO(OR4)2and -COOH; R4independently represent H; L is C1-C6alkylene, optionally interrupted by one or more groups -N(R'2)-, R'2independently represents what is defined for R2. Invention also relates to a chelated complex, to a pharmaceutical composition for diagnostic imaging of an organ or tissue of a human or animal body using an MRI method, to a compound of formula (I), wherein each of carboxyl groups of R groups bonded with nitrogen atoms of macrocycles is in protected form in form of tert-butyl ether.EFFECT: there are prepared new compounds of formula (I), which are used as contrast agents possessing increased relactivity.19 cl, 1 tbl, 6 ex |
| priorityDate | 2015-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.