http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2739761-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52490458f9d42fb58ffd4beb4bbbc310 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5517 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5517 |
| filingDate | 2018-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c296d86d7e221c8fab748ecced388b09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4fa7e621a739ad87ae5eb5dc9da5ff2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33fb07fa7e514303c05972ffc896fa29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70236fec9aac30da197a5658e20632a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83be1657ab26c38f3760001992dc66a5 |
| publicationDate | 2020-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2739761-C2 |
| titleOfInvention | Method of producing n-alkyl-n-{[3-alkyl-3,8-diazabicyclo[3_2_1]octa-1(7),5-dien-8-yl]methyl}amines and use thereof as antimicrobial activity agents |
| abstract | FIELD: chemistry.SUBSTANCE: present invention relates to novel N-alkyl-N-{[3-alkyl-3,8-diazabicyclo[3.2.1]octa-1(7),5-dien-8-yl]methyl}amines of general formula (1)to a method for production thereof and to use thereof as agents with antimicrobial activity in relation to Staphylococcus aureus, Escherichia coli, Acinetobacter baumannii, Candida albicans, Cryptococcus neoformans, Klebsiella pneumoniae. Method of obtaining is that pyrrole is reacted with pre-prepared at 60 °C for 2 hours in a solution of methanol with a mixture of paraformaldehyde and an amine of general formula R-NH2, (where R is specified above), the reaction is carried out in the presence of ZrOCl2·8H2O catalyst in molar ratio of pyrrole:primary amine:paraformaldehyde:ZrOCl2·8H2O = 1:2:3:(0.03–0.07) at temperature 0 °C and atmospheric pressure for 5–7 hours.EFFECT: disclosed are a method of producing N-alkyl-N-{[3-alkyl-3,8-diazabicyclo[3_2_1]octa-1(7),5-dien-8-yl]methyl}amines and use thereof as agents with antimicrobial activity.3 cl, 2 tbl, 7 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2790377-C1 |
| priorityDate | 2018-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.