http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2739686-C1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1a924922a8709cb042444536b354ff26 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
filingDate | 2020-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01d216ea2f2593729e991beb366a5219 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0959596a2f4699923c549441acd81083 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe679fdc28a5d29b98817ca84a050222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d28bff386926e7e2b293849ef22af12d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0d0121ad6611d44d5de53515aa70eb6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54f850ca5dc188e33ba60829e11df321 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7aef61794d0690898f5bcb8730f9568f |
publicationDate | 2020-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2739686-C1 |
titleOfInvention | Method for evaluating congenital immunity in patients with recurrent exudative otitis media |
abstract | FIELD: medicine.SUBSTANCE: invention refers to medicine, particularly to otorhinolaryngology. What is presented is a method for estimating congenital immunity in the patients with recurrent exudative osteitis and obstruction of the auditory tube. In exudate of tympanic cavity by means of polymerase chain reaction in real time level of expression of the gene of pro-inflammatory cytokine IL1β is determined and level of expression of antimicrobial peptide HBD1, HBD2 genes. If observing the following conditions simultaneously: IL1β expression level - from 50 rel. units and higher, expression level of HBD1 - from 2 rel. units and higher, level of expression of HBD2 - from 10 rel. units and higher - congenital immunity is diagnosed.EFFECT: invention provides developing a diagnostic technique for detecting a defect of innate immunity in patients with recurrent exudative osteitis in order to select patients for immunocorrective therapy and assessing the prospects of further treatment.1 cl, 3 dwg, 1 tbl, 2 ex |
priorityDate | 2020-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.