http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2739198-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e488452f75d5486fdfde9ccc93fea4e8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
| filingDate | 2017-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c50dbf3a5467f7561893780a4a6600a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ceb9b3d742f8859f782359cc8d9ac95d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_835fac3c54c137938340a263cbbbf4ec |
| publicationDate | 2020-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2739198-C2 |
| titleOfInvention | Boron-containing compound |
| abstract | FIELD: pharmaceuticals.SUBSTANCE: invention relates to a novel boron-containing compound, specifically to a compound corresponding to following formula 1, or a pharmaceutically acceptable salt thereof, selected from an alkali metal salt, ammonium salts, tetraalkylammonium salts (NR4+) or tetraphenylphosphonium salts:[Formula 1]In formula 1: black circle denotes atom B, white circle denotes BH; -R1denotes -(CH2)-n-X1-R3(n denotes integer from 0 to 6; X1denotes O-CO, or absent; R3denotes C6-C20alkyl, hydroxy C6-C20alkyl, amino C6-C20alkyl, azido C6-C20alkyl, hydroxycarbonyl C6-C20alkyl, substituted, where the substitutes are nitro, hydroxyl, B(OH)2, or unsubstituted phenoxy C6-C20alkyl, substituted, wherein the substituent is dioxyfenylxanten, phenylthiourea or unsubstituted C6-C20alkyl or unsubstituted benzyl group) or a group having a repeating sequence -(CH2)2-O- 3 times or more and 10 times or less and having a methyl group or an ethyl group on the end from the oxygen atom side; -R2denotes -(CH2)m-X2-R4(m denotes integer from 0 to 8; X 2 denotes O, NH, NHCO or absent; R4denotes a tumor-recognizing portion selected from a group consisting of an amino acid, amino acid amide, 5-aminolevulinic acid, kojic acid, hydroquinone, resveratrol, ligand TSPO (translocating protein) of DPA type (acetyl amide of dimethyl pyrazolopyrimidine), caffeic acid or its salts, monosaccharides, and nucleic acids or their salts). Also disclosed are methods of producing boron-containing compounds and a pharmaceutical composition.EFFECT: disclosed boron-containing compound can be used for treating a malignant tumor using a boron neutron capture technique (BNCT).13 cl, 7 tbl, 4 ex, 3 dwg |
| priorityDate | 2016-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 193.