http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2738975-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_38b4359287cd465f1367c4b6ac87218e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2020-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_075b764c6b03879ed0882b12c2d2ba30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4541ebfa99fb7d105f97b1b0140b1299 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_052ec034468195a6bdc4a032539e189e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcdccc68b866b57c974e735357a9c86b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_563f3c04639363a4271099880c987a46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cf7189e2441cd9b69e8ac0f1848407d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6037d9051f47b3c118c54d7ddbaf5951 |
| publicationDate | 2020-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2738975-C1 |
| titleOfInvention | Method for liability to development of atherosclerosis in middle-aged men |
| abstract | FIELD: biotechnology.SUBSTANCE: invention refers to biotechnology, namely to early diagnostics of atherosclerosis. Buccal epithelial sample is taken from the patient and deoxyribonucleic acid DNA is extracted from said sample. On a detecting amplifier using polymerase chain reaction carried out a genotyping of polymorphism of FAS and MMP9 genes using a DNA segment as a primer by examining the genotypes of the FAS gene (Rs1159120) and the MMP9 gene (rs17576). Content of triglycerides is determined in a blood sample. And with simultaneous meeting the following conditions: presence of a combination of a gene of FAS gene (rs1159120) CC genotype, as well as genotype AA of gene MMP9 (rs17576), with simultaneous excess triglycerides in blood above upper limit of physiological norm in 1.15–2.15 times, risk of developing atherosclerosis in middle-aged men is considered to be high.EFFECT: invention provides reliable diagnosis of prediction of the risk of developing atherosclerosis in middle-aged men (36–45 years).1 cl, 1 tbl, 2 ex |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2803075-C1 |
| priorityDate | 2020-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 252.