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filingDate 2020-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccf2631d164a6fc51f914c7a0b063e39
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publicationDate 2021-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2737503-C9
titleOfInvention Method of personified prediction of clinical effectiveness of non-alcoholic fatty liver disease in patients with metabolic syndrome
abstract FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to internal diseases, and can be used to select personified prediction of clinical effectiveness of non-alcoholic fatty liver disease in patients with metabolic syndrome. Method of personified prediction of clinical effectiveness of non-alcoholic fatty liver disease in patients with ursodeoxycholic acid syndrome in a daily dosage of 15 mg per kg of body weight divided into 3 doses (after breakfast, after lunch and after dinner) in combination with Rosuvastatin 10 mg a day (after dinner) within 6 months includes determining initial values of alanine aminotransferase (ALT, units/l); level of C-reactive protein (CRP, mg/l); atherogenic index (AI) level; insulin resistance index (IR) level; level of diastolic arterial pressure (APd, mm Hg) and solving the discriminant equation: D=0.157×ALT+0.127×CRP+0.286×AI+0.515×IR+0.034×APd-10.948, where D is a discriminant function with its boundary value equal to zero, wherein if D is less than or equal to zero, a positive clinical outcome is predicted, and if D is greater than zero, a negative clinical outcome is predicted.EFFECT: invention provides higher accuracy of personalized prediction of clinical effectiveness of non-alcoholic fatty liver disease.1 cl, 2 ex
priorityDate 2020-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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