http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2737220-C1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79ae6dd5bafbd2dd69035367385d754c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-72 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 |
filingDate | 2019-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0aa9bc520c10e3b375912581eb99bd12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ba0cd89e26f5890c06642ae393532bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48e31b70497a9e1225138cec78ac3ba6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16e4325365d62443551d569f52c0ddc0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f299a0345189039bb094535883cd7927 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8aa3a6a98f2924d83c1686e60de350e1 |
publicationDate | 2020-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | RU-2737220-C1 |
titleOfInvention | Method for differentiating cervical neoplasia by lipid composition of tissue |
abstract | FIELD: medicine; gynecology. n SUBSTANCE: invention can be used for differentiating cervical neoplasms by lipid composition of tissue. For this purpose mass spectrometry is used to determine lipid profile of tissue using OPLS-DA method and using OPLS model, based on the following lipid levels: phosphatidylcholines (PC 32:0, PC 34:1, PC 36:4, PC 34:0, PC 38:4), ethanolamines (PE O-46:0, LPE 46:0, PE O-48:0, LPE 48:0, PE O-46:1) and sphingomyelins (SM 34:0, SM 42:2), estimated parameter (EP) is calculated by proposed formula. If EP<−0.5, tissue is considered to correspond to epithelium of UC with chronic cervicitis; at a value of −0.5<EP<0, the conclusion is made that tissue corresponds to epithelium of UC with LSIL; if value 0<EP<1, the tissue corresponds to the UC epithelium with HSIL; if EP>1, tissue is considered to correspond to cervical cancer epithelium. n EFFECT: method enables high-accuracy differentiation of different types of neoplastic process in epithelium of cervix uteri. n 1 cl, 6 ex, 6 dwg |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2773799-C1 |
priorityDate | 2019-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.