http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2736483-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7e727c9f4676aee16b1a224b8ffd323 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F257-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F257-00 |
| filingDate | 2019-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b45e1fae59cb31655ac40e138a53178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48347bc3a7cd6316f0c6b9fb6aa19c77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb0af8fc4d7c652f91accaccb06d8e14 |
| publicationDate | 2020-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2736483-C1 |
| titleOfInvention | Method of producing luminescent regularly polyfluorene molecular brushes with side chains of water-soluble heat-sensitive biocompatible polymers |
| abstract | FIELD: chemistry.SUBSTANCE: invention relates to chemistry of high-molecular compounds, specifically to a method of producing luminescent regularly grafted polyfluorene molecular brushes with side chains of water-soluble heat-sensitive biocompatible polymers by using a "grafting through" method for polycondensation, consisting in that polycondensation of fluorene macromonomer(s) (4–6 wt. %), including (them) side polymer chains of a future molecular brush of water-soluble heat-sensitive biocompatible polymers, which is 2,7-dibromofluorene with chains of polyalkyloxazoline or oligoethylene glycol attached to it in position 9,9, and second monomer (0.5–3 wt. %) - 2,7-pinacolone ester of diboronic acid-9,9-dihexyl-fluorene or 2,7-pinaclin dibonoic acid ester-9,9-dioctyl-fluorene, at ratio of macromonomer(s): second monomer = 1:1 in a solution of N,N-dimethylformamide in an atmosphere of an inert gas in the presence of catalyst - 1,1'-bis(diphenylphosphino)ferrocene palladium (II) chloride (0.25–0.35 wt. %), and 0.2M potassium carbonate solution (30–35 vol. %) in a microwave reactor at 95–100 °C and power 100 W for 1–1.5 hours, after completion of reaction solution is purified by fractional precipitation with subsequent centrifugation, purification is performed from residues of low-molecular and oligomeric impurities by dialysis for 2 days and centrifuging solution in test tube with membrane of porous regenerated cellulose, freezing solution and lyophilic drying for 2 days, obtaining hygroscopic preserved in exsicitor target product - luminescent molecular brush with link formula:where p, k is molar fraction: p + k = 1, p = 0–1, k = 0–1; y = 3, 6; Mw= 120–380 kDa.EFFECT: technical result: method of producing molecular brushes by "grafting through" method, characterized by high output of target product and high density of grafts.1 cl, 12 ex, 4 dwg |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2800291-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2777171-C1 |
| priorityDate | 2019-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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