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filingDate 2019-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_629fecb54453892c72c5108dee5c5cb1
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publicationDate 2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2735664-C2
titleOfInvention Method for combined production of 3'-substituted spiro[3,9-dioxatetracyclo[5_3_2_02,4_08,10]dodec-5-ene-11,2'-oxiranes] and spiro[3,9-dioxatetracyclo[5_3_2_02,4_08,10]dodec-5-en-12,2'-oxiranes] exhibiting antitumour activity
abstract FIELD: chemistry. n SUBSTANCE: invention relates to 3'-substituted spiro[3,9-dioxatetracyclo[5.3.2.0 2,4 .0 8,10 ]dodec-5-en-11,2'-oxiranes] of formula (1) and spiro[3,9-dioxatetracyclo[5.3.2.0 2,4 .0 8,10 ]dodec-5-en-12,2'-oxiranes of formula (2), where R = Ph, Hex. Invention also relates to a method for combined production of said compounds, which involves reacting bicyclo[4.2.2]deca-2,4,7-trienes with m-chloroperoxybenzoic acid at temperature of 0–40 °C, in dichloromethane for 3–23 hours n n n n EFFECT: technical result is a method of producing novel compounds which can be used in medicine as biologically active substances having antitumour activity. n 2 cl, 2 tbl, 3 ex, 1 dwg
priorityDate 2019-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 48.