abstract |
FIELD: medicine; pharmaceuticals. n SUBSTANCE: group of inventions relates to a combination for treating prostate cancer, comprising (i) one of a benzoheterocyclic compound, a pharmaceutically acceptable salt thereof, a stereoisomer, an isotopic compound and (ii) a androgen receptor path modulator, and in some embodiments further comprising an agent selected from abiraterone, abiraterone acetate, galeterone, ODM201, prednisone or combinations thereof, as well as to a pharmaceutical composition and kit for treating prostate cancer, use of said compounds in preparing a medicament for preventing and/or treating prostate cancer, and to a method of preventing and/or treating prostate cancer. n EFFECT: inventions of the group provide inhibition of prostate cancer more effectively. n 16 cl, 4 tbl, 1 ex |