abstract |
FIELD: medicine. n SUBSTANCE: invention relates to use of a combination comprising (a) B7-H3 antibody or antigen-binding fragment thereof, wherein said B7-H3 antibody or antigen-binding fragment thereof is administered in a dose of about 1–15 mg/kg of body weight, and (b) an anti-PD-1 antibody or antigen-binding fragment thereof for treating cancer in a subject in need thereof. n EFFECT: invention provides intensified anticancer activity. n 46 cl, 1 ex, 6 tbl |