http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2726926-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79ae6dd5bafbd2dd69035367385d754c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G09B23-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G09B23-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G09B23-28 |
| filingDate | 2019-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5473cf97335c11fb46719f2c26dcff0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e8d05941e675cccf1bd8fe4074b25d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c86c655e0c19a13f231c6818af3422b0 |
| publicationDate | 2020-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2726926-C1 |
| titleOfInvention | Method for simulating toxic heart involvement in rats |
| abstract | FIELD: medicine.SUBSTANCE: invention refers to experimental medicine and pharmacology and can be used for studying the toxic effect on the cardiac conduction system in pre-clinical study of new cardioprotective agents, studying mechanisms of their action and developing new methods of treatment. A method for modeling toxic cardiac involvement in rats involves toxic cardiac involvement in animals by daily at least 2 weeks of administration of a complex of antituberculous preparations moxifloxacin, bedaquiline, linezolid, protionamide and capreomycin, rat females aged 10–12 months and weighing 330–350 g used for modeling.EFFECT: invention provides good reproducibility, absence of lethal outcome of experimental animals and short period of development of pathological condition.5 cl, 3 dwg, 3 tbl |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2794488-C1 |
| priorityDate | 2019-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.