| abstract |
FIELD: medicine; pharmaceuticals. n SUBSTANCE: described are pharmaceutical compositions for preventing or treating a cardiovascular disease comprising amlodipine, rosuvastatin and losartan, and a pharmaceutical complex composition, including a first mixture containing amlodipine and rosuvastatin, and a second mixture containing losartan. n EFFECT: composition and complex composition include rosuvastatin having particle size (D 90 ) of 50 mcm or less, and exhibit an excellent dissolution rate, bioavailability, stability and uniformity of the content, and can therefore be useful in the pharmaceutical industry. n 9 cl, 6 tbl, 5 dwg |