http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2722669-C1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e0df9e526e2427a4525daa89ab2232f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate | 2019-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_add1d0b53b6dd1bab44634f19b380b6f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92f853702934598347737c4ebae828c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c1be39a2f2dfb331f3f2f0ce6f84b60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f96d01f1a1a6e1dfb80ae425d7eba2fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b12efeecb54e35f968e1816a0c10fdf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02f86e68c1624ec5f883ff540fdd9ef3 |
| publicationDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2722669-C1 |
| titleOfInvention | Method for producing associates of hematopoietic and stromal progenitor cells capable of suppressing activation and proliferation of allogenic lymphocytes |
| abstract | FIELD: biotechnologies. n SUBSTANCE: invention relates to the biotechnology. Described is a method for producing associates of hematopoietic and stromal progenitor cells. Preparation of stromal sublayer of MSC from stromal-vascular fraction of adipose tissue with stop of cell divisions with mitomycin C, mononuclear fraction of umbilical blood is added and are co-cultivated for 144 hours to obtain associates of HSPC with atMSC, capable also effectively, as atMSC in monoculture, to suppress activation and proliferation of allogenic lymphocytes. Method enables producing associates of hematopoietic stem and progenitor cells of umbilical cord blood (HSPC) and atMSC, in which the population of HSPC is more than by 80 % presented by precursor cells with complex phenotype CD34 + /CD133 + associated with stromal sublayer atMSC. n EFFECT: invention can be used for producing associates, in which multipotent mesenchymal stromal cells from adipose tissue (atMSC) retain immunosuppressive activity. n 4 cl, 4 dwg, 2 tbl, 1 ex |
| priorityDate | 2019-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 151.