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filingDate 2016-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd9d32992dc005f2255be2b37a0df3f1
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publicationDate 2020-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber RU-2721396-C2
titleOfInvention Physically and chemically stable oral suspension of givinostat
abstract FIELD: medicine; pharmaceuticals.SUBSTANCE: invention relates to aqueous suspensions. Described is an aqueous suspension for treating a disease responding to histone deacetylase inhibitors, containing givinostat and/or its pharmaceutically acceptable salts, at least a wetting agent, at least a substance, imparting a density, at least a buffer agent and at least a suspending agent; where wetting agent is sorbitan fatty acid polyoxyethylene ester, poloxamer or a mixture thereof, the substance imparting a density, is sucrose, sorbitol or a mixture thereof, and the buffer agent is a phosphate buffer, a citrate buffer or a tartrate buffer, and the suspending agent is tragacanth gum or guar gum.EFFECT: technical result is suspensions have stability in time and have attractive taste.15 cl, 12 tbl, 9 ex
priorityDate 2015-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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