http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2717956-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75b86e50a7529f6158517db14a0b81df |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-7057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6878 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6845 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6804 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542 |
| filingDate | 2015-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a42b7947c5a88824c7bfa030827a17f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58aedf593c520c081c3f77619c93a241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98190ca295bfc9e633ecf2f741177c7a |
| publicationDate | 2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | RU-2717956-C2 |
| titleOfInvention | Method for detecting spatial proximity of first and second epitopes |
| abstract | FIELD: medicine.SUBSTANCE: group of inventions refers to medicine and concerns a method for detecting spatial proximity of the first and second protein epitopes or the first and second proteins of a protein complex in a patient's sample involving binding a first antibody or an antibody fragment having a first oligonucleotide conjugated to it, with a first epitope, binding a second antibody or antibody fragment having a second oligonucleotide conjugated to it with a second epitope, and determining whether a resonant fluorescence energy transfer effect is present, wherein the first oligonucleotide is at least partially complementary to the second oligonucleotide, the first oligonucleotide is initially provided with a first separate protective element and/or the second oligonucleotide is initially provided with a second separate protective element. Group of inventions also relates to a method of stratifying a patient suffering from a disease, to assess fitness of treatment, where treatment is directed to a signalling path; kit for implementing said methods.EFFECT: group of inventions provides high sensitivity of spatial proximity detection of first and second epitopes.14 cl, 6 dwg, 1 ex |
| priorityDate | 2014-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.