| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-454
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-454
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2016-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57b331bff02790d706d855e1733bed7c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_601f3db1aa761e803876839f8b68d190 |
| publicationDate |
2020-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
RU-2717564-C2 |
| titleOfInvention |
Crystalline forms of 1-((2r,4r)-2-(1h-benzo[d]imidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate |
| abstract |
FIELD: chemistry. n SUBSTANCE: invention relates to organic chemistry and specifically to crystalline form of maleate 1-((2R,4R)-2-(1H-benzo[d]imidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyano-phenyl)urea, which has X-ray powder diffraction pattern including peaks at 2θ: 11.6, 12.1 and 19.6 °2θ ± 0.2 °2θ. Also described is a pharmaceutical composition based on the crystalline form of said urea maleate. n n n n EFFECT: technical result is obtaining urea maleate, which has improved chemical and thermal stability during storage, low hygroscopicity while maintaining chemical and enantiomeric stability. n 12 cl, 7 ex, 8 tbl, 5 dwg |
| priorityDate |
2015-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |