abstract |
FIELD: biotechnology.SUBSTANCE: disclosed is a composition containing one or more viral vectors coding CRISPR/Cas system for use in treating a disease or cerebral disorder.EFFECT: said system due to the presence of at least one nuclear localization signal (NLS) enables efficient editing of the eukaryotic cell genome, in connection with which it can be used to edit genes associated with cerebral diseases in mammals.20 cl, 85 dwg, 18 tbl, 40 ex |